Triethylamine → HCID 44226153, 화합물

HRID 1359935

반응식

HRID 1359935 반응식
[P:1]([Cl:12])(Cl)([O:3][C:4]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][CH:5]=1)=[O:2].Cl.[CH2:14]([O:16][C:17](=[O:21])[C@H:18]([CH3:20])[NH2:19])[CH3:15].CCN(CC)CC>C(Cl)Cl>[Cl:12][P:1]([NH:19][C@H:18]([C:17]([O:16][CH2:14][CH3:15])=[O:21])[CH3:20])([O:3][C:4]1[CH:5]=[CH:6][C:7]([Cl:10])=[CH:8][CH:9]=1)=[O:2]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 69879p-Chlorophenyl dichlorophosphateHCID 2724356L-Alanine, ethyl ester, hydrochloride (1:1)

생성물 1

HCID 44226153HCID 44226153, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.090 M) of 4-chlorophenyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1:1* mixture of diastereoisomers.

출처 및 근거

ORD 기록
ord-3ddd7d4e011440eb9d7c77cc15a78b39
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07879815B2

연결된 노트

불러오는 중…