Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → n-Butyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | p-Chlorophenyl dichlorophosphate | HCID 69879 | — |
| 반응물 | L-Alanine, ethyl ester, hydrochloride (1:1) | HCID 2724356 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | n-Butyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate | HCID 59157902 | — |
반응 단계
Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.090 M) of the commercially available 4-chlorophenyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1.1:1* mixture of diastereoisomers. 31P NMR (400 MHz, CDCl3): δ: 9.52 and 9.28*
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07879815B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-eaedf7c015764052a90ad976cd877017 |
| 출처 메모 | uspto-grants-2011_02 |