4-Iodophenol → 2-(4-Iodophenoxy)-5-ethylpyrimidine

HRID 1360035

반응식

[I:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[CH2:9]([C:11]1[CH:12]=[N:13][C:14](Cl)=[N:15][CH:16]=1)[CH3:10].C(=O)([O-])[O-].[K+].[K+]>>[I:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:14]2[N:15]=[CH:16][C:11]([CH2:9][CH3:10])=[CH:12][N:13]=2)=[CH:4][CH:3]=1

참가 물질

반응물 3

HCID 108944-Iodophenol

HCID 11430Potassium Carbonate

HCID 35727632-Chloro-5-ethylpyrimidine

생성물 1

HCID 577625172-(4-Iodophenoxy)-5-ethylpyrimidine

실험 절차

In the same manner as in Reference Example 6, 4-iodophenol (220 mg) and 5-ethyl-2-chloropyrimidine (0.121 ml) were reacted in the presence of potassium carbonate (415 mg) to obtain 2-(4-iodophenoxy)-5-ethylpyrimidine (256 mg).

출처 및 근거

ORD 기록: ord-9e7a6c8529c94cb1abe5aba2c736ee59
출처 데이터셋: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07879837B2

연결된 노트

불러오는 중…