Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776300, 화합물

HRID 1361546노트

반응식

HRID 1361546 반응식
[CH3:1][O:2][CH2:3][C@H:4]([CH3:26])[O:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([O:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=2)[CH:14]=1)[C:9](O)=[O:10].[CH2:27]([O:29][C:30](=[O:39])[CH2:31][S:32][C:33]1[S:37][C:36]([NH2:38])=[N:35][CH:34]=1)[CH3:28]>>[CH2:27]([O:29][C:30](=[O:39])[CH2:31][S:32][C:33]1[S:37][C:36]([NH:38][C:9](=[O:10])[C:8]2[CH:12]=[C:13]([O:15][C:16]3[CH:21]=[CH:20][C:19]([C:22]([F:24])([F:25])[F:23])=[CH:18][CH:17]=3)[CH:14]=[C:6]([O:5][C@@H:4]([CH3:26])[CH2:3][O:2][CH3:1])[CH:7]=2)=[N:35][CH:34]=1)[CH3:28]

참가 물질

3

반응물 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 66969999HCID 66969999, 화합물

생성물 1

HCID 57776300HCID 57776300, 화합물

실험 절차

The title compound was prepared from 3-((S)-2-methoxy-1-methyl-ethoxy)-5-(4-trifluoromethyl-phenoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

출처 및 근거

ORD 기록
ord-128ee0869b364f58b1d6cd9cc7a7c9cb
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07880012B2

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