1,3-dimethyl-1H-indole-2-carboxylate → HCID 22138996, 화합물

HRID 1361992노트

반응식

HRID 1361992 반응식
BrC1C=C[C:5](NCC(OC)=O)=[N:6]C=1.[CH3:14][N:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][C:22]=2[CH3:24])[C:17]([C:25]([O-])=O)=[CH:16]1.CN1C2C(=CC=CC=2)C(C)=C1C([O-])=O>>[CH3:14][N:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][C:22]=2[CH3:24])[C:17]([CH2:25][NH:6][CH3:5])=[CH:16]1

참가 물질

4

반응물 3

HCID 221390101,3-dimethyl-1H-indole-2-carboxylateHCID 22139049Methyl 2-((5-bromopyridin-2-yl)amino)acetateHCID 22139074HCID 22139074, 화합물

생성물 1

HCID 22138996HCID 22138996, 화합물수율 98%

실험 절차

According to the procedure of Preparation 13 (c), except substituting 1,7-dimethyl-1H-indole-3-carboxylate for the 1,3-dimethyl-1H-indole-2-carboxylate, the title compound (0.74 g, 98%) was obtained as an amber oil: MS (ES) m/e 189.2 (M+H)+.

출처 및 근거

ORD 기록
ord-ada6110ae4b74be382ba8ff9c49ecf4f
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07879872B2

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