Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2,3-Difluorophenyl propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Propionyl chloride | HCID 62324 | — |
| 반응물 | 2,3-Difluorophenol | HCID 80879 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2,3-Difluorophenyl propionate | HCID 66969490 | 105.2% |
반응 단계
20 g (153.7 mmol) of 2,3-difluorophenol in 150 ml of dichloromethane and 17.5 ml of pyridine are admixed dropwise at 0° C. with 14 ml (161 mmol) of propionyl chloride. The mixture is stirred for two hours and 100 ml of 2 M hydrochloric acid are added. The mixture is extracted with dichloromethane and the extracts are washed with water. Drying over sodium sulphate and the removal of the solvent in vacuo give 30.1 g of 2,3-difluorophenyl propionate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07880042B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-f81e89d20163424890f98d077e8c1f16 |
| 출처 메모 | uspto-grants-2011_02 |