Phenylboronic Acid → N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

반응식

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:15])=[O:14])[CH2:5]2.[C:22]1(B(O)O)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:5]3)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

참가 물질

반응물 2

HCID 66827Phenylboronic Acid

HCID 18177113N-(6-Bromo-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

생성물 1

HCID 17758907N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

실험 절차

Compound 170A was prepared from 87A and phenylboronic acid by procedures analogous to those described in Example 91A.

출처 및 근거

ORD 기록: ord-0dd0731e8f40416b9630714aa0eb7493
출처 데이터셋: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07884113B2

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