1,3-Cyclohexanedione → 2-Bromocyclohexane-1,3-dione

HRID 1364080노트

반응식

HRID 1364080 반응식
[C:1]1(=[O:8])[CH2:6][CH2:5][CH2:4][C:3](=[O:7])[CH2:2]1.[Br:9]Br>CC(O)=O>[Br:9][CH:2]1[C:3](=[O:7])[CH2:4][CH2:5][CH2:6][C:1]1=[O:8]

참가 물질

4

반응물 2

HCID 104341,3-CyclohexanedioneHCID 24408Bromine

생성물 1

HCID 27704762-Bromocyclohexane-1,3-dione

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

To a stirred solution of cyclohexane-1,3-dione (1.12 g, 10 mmol) in AcOH (20 mL) at r.t. was added bromine (1.6 g, 0.51 mL, 10 mmol) dropwise. The reaction mixture was stirred for 2 h and then the product was isolated by filtration. The precipitate was washed twice with Et2O (100 mL) and then dried in vacuo to give the title compound in quantitative yield as a buff solid, which was used without further purification. LCMS (ES+) 190.9 (M+H)+.

후처리

  1. customthe product was isolated by filtration
  2. washThe precipitate was washed twice with Et2O (100 mL)
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-71186469f40b42658d4deaa0c35056b0
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07888344B2

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