N-(2-allyl-4-fluoro-phenyl)-acrylamide → HCID 57779786, 화합물
반응식
[CH2:1]([C:4]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:5]=1[NH:11][C:12](=[O:15])[CH:13]=[CH2:14])C=C>ClCCl>[F:10][C:8]1[CH:7]=[CH:6][C:5]2[NH:11][C:12](=[O:15])[CH:13]=[CH:14][CH2:1][C:4]=2[CH:9]=1참가 물질
3
실험 절차
A round-bottom flask containing the product from Step 2 (4.51 g, 21.9 mmol) was fitted with a stirbar and septa. Dichloromethane (800 mL) and Zhan catalyst I (0.735 g, 1.11 mmol) were added, and the resulting solution was stirred for 18 hours at room temperature. The reaction was then concentrated in vacuo and recrystallized from dichloromethane to give the desired product.
후처리
- customwas fitted with a stirbar and septa
- concentrationThe reaction was then concentrated in vacuo
- customrecrystallized from dichloromethane
출처 및 근거
- ORD 기록
- ord-3acdda58df154d9586e72789305e7edf
- 출처 데이터셋
- uspto-grants-2011_02
- 특허 번호
- US07888345B2
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