Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
methyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoate → Methyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | methyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoate | HCID 57670914 | — |
| 반응물 | 3-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acid | HCID 57671085 | — |
| 반응물 | 4-(Tert-butoxycarbonyl)benzenesulfonamide | HCID 59733636 | — |
| 반응물 | Tert-butyl 3-sulfamoylbenzoate | HCID 59733695 | — |
| 반응물 | 4-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acid | HCID 66934750 | — |
| 생성물 | Methyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoate | HCID 57670935 | — |
반응 단계
4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acid, synthesized by using 4-(tert-butoxycarbonyl) benzenesulfonamide instead of the starting material compound of Example 198, that is, 3-(tert-butoxycarbonyl) benzenesulfonamide for the similar procedure as in Example 198, was used instead of the starting material of Example 208, that is, the compound 196, for the similar procedure as with Example 208 to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07888348B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-68855360b0b74fcfacaed3868fc551e8 |
| 출처 메모 | uspto-grants-2011_02 |