Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 7-Methoxy-2,3-dihydrobenzofuran-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | 7-Methoxybenzofuran-3(2H)-one | HCID 2818112 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 7-Methoxy-2,3-dihydrobenzofuran-3-ol | HCID 65721420 | 100% |
반응 단계
To a cold (ice water) solution of 7-methoxy-3-(2H)-benzofuranone (846 mg; 5.0 mmol) in methanol (5 mL) is added sodium borohydride (179 mg; 5.0 mmol) is stirred for 15 minutes. Water (5 mL) is added to the solution and stirred 15 minutes. Saturated ammonium chloride (20 mL) is added and the solution is extracted with ethyl acetate. The organics are separated and dried over magnesium sulfate. The solvent is removed to give 831 milligrams of 7-methoxy-2,3-dihydrobenzofuran-3-ol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07888366B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-f638ed0f431b4ab7a44b77ffdd28ddb3 |
| 출처 메모 | uspto-grants-2011_02 |