5-Methanesulfonylthiophene-2-carboxylic acid → HCID 58614768, 화합물

HRID 1364637노트

반응식

HRID 1364637 반응식
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[CH3:15][S:16]([C:19]1[S:23][C:22]([C:24](O)=[O:25])=[CH:21][CH:20]=1)(=[O:18])=[O:17]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:24]([C:22]2[S:23][C:19]([S:16]([CH3:15])(=[O:18])=[O:17])=[CH:20][CH:21]=2)=[O:25])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

참가 물질

3

반응물 2

HCID 27404975-Methanesulfonylthiophene-2-carboxylic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

생성물 1

HCID 58614768HCID 58614768, 화합물

실험 절차

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline (40 mg) and 5-(methylsulfonyl)thiophene-2-carboxylic acid to produce N-(4-chloro-3-(pyridin-2-yl)phenyl)-5-(methylsulfonyl)thiophene-2-carboxamide. MS (Q1) 393.0 (M)+.

출처 및 근거

ORD 기록
ord-4067d0802fe6468e9731f377ed07aa13
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07888364B2

반응 노트

불러오는 중…