2-Aminonicotinic acid → 2-amino-N-(4-chloro-3-(pyridin-2-yl)phenyl)pyridine-3-carboxamide

HRID 1364645

반응식

HRID 1364645 반응식
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[NH2:15][C:16]1[N:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](O)=[O:19]>>[NH2:15][C:16]1[C:17]([C:18]([NH:6][C:5]2[CH:7]=[CH:8][C:2]([Cl:1])=[C:3]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=3)[CH:4]=2)=[O:19])=[CH:21][CH:22]=[CH:23][N:24]=1

참가 물질

3

반응물 2

HCID 729302-Aminonicotinic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

생성물 1

HCID 586148602-amino-N-(4-chloro-3-(pyridin-2-yl)phenyl)pyridine-3-carboxamide

실험 절차

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline (50 mg) and 2-aminonicotinic acid to produce 2-amino-N-(4-chloro-3-(pyridin-2-yl)phenyl)pyridine-3-carboxamide. MS (Q1) 325.2 (M)+.

출처 및 근거

ORD 기록
ord-2f98b321ba2840ccb91276b9971c1ec9
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07888364B2

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