Benzaldehyde → 2-Phenylbenzothiazole

HRID 1365592

반응식

HRID 1365592 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C1(C)C(C)=CC=CC=1>[C:10]1([C:9]2[S:8][C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[N:1]=2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

참가 물질

4

반응물 2

HCID 240BenzaldehydeHCID 87132-Aminothiophenol

생성물 1

HCID 134392-Phenylbenzothiazole

시약·촉매·용매 1

HCID 7237O-Xylene용매

반응 조건

온도
120 °C

실험 절차

2-Aminothiophenol (0.856 ml, 8 mmol), benzaldehyde (0.813 ml, 8 mmol), 1 g of an oxidation catalyst and 15 ml of xylene as solvent were charged into a 100 ml three-neck flask, and were stirred at 120° C. for 13 hours under an oxygen atmosphere. The reaction mixture was filtered through Celite, and then the Celite and the oxidation catalyst were washed with ethyl acetate. The filtrate was condensed with a rotary evaporator to yield a solid. The solid was recrystallized from diethyl ether. Resulting colorless crystals were then weighed and the yield thereof was defined as a reaction yield.

후처리

  1. filtrationThe reaction mixture was filtered through Celite
  2. washthe Celite and the oxidation catalyst were washed with ethyl acetate
  3. customcondensed
  4. customwith a rotary evaporator
  5. customto yield a solid
  6. customThe solid was recrystallized from diethyl ether
  7. customResulting colorless crystals
  8. customthe yield
  9. customyield

출처 및 근거

ORD 기록
ord-d61abc7cb7ff4475a705cec8cd41030f
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07893004B2

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