Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → 1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | 5-(3-Chlorophenyl)furfural | HCID 609822 | — |
| 반응물 | HCID 178418689 | HCID 178418689 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-ol | HCID 62498593 | — |
반응 단계
To a solution of 5-(3-chlorophenyl)furan-2-carbaldehyde (1.0 equiv.) in THF at 0° C. was added MeMgBr in ether (3.0 equiv.) and stirred for 45 min. The reaction was quenched with water, diluted with ether and filtered through Celite. The organic layer was separated and washed with brine, dried over MgSO4, and concentrated to give the 1-[5-(3-chlorophenyl)-2-furyl]ethan-1-ol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07893096B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-ef510c6e17114ee2bb54dac234e3a116 |
| 출처 메모 | uspto-grants-2011_02 |