[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][C:9](=[O:11])[CH2:8][C@H:7]1[C:12]([OH:14])=O)=[O:5])[CH3:2].Cl.[NH2:16][C:17]1([C:20]#[N:21])[CH2:19][CH2:18]1>>[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][C:9](=[O:11])[CH2:8][C@H:7]1[C:12](=[O:14])[NH:16][C:17]1([C:20]#[N:21])[CH2:19][CH2:18]1)=[O:5])[CH3:2]The reaction of (1R,2R)-4-oxo-cyclopentane-1,2-dicarboxylic acid monoethyl ester and 1-amino-cyclopropanecarbonitrile hydrochloride performed in analogy to example 1, step 8 yielded the title compound as a colorless solid. MS: 265.1 (M+H)+.
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