Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethyl orthoacetate → 4(3H)-Quinazolinone, 2-methyl-3-(2-pyridyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethyl orthoacetate | HCID 66221 | — |
| 반응물 | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4(3H)-Quinazolinone, 2-methyl-3-(2-pyridyl)- | HCID 64049 | 75% |
반응 단계
A mixture of 72 (3 g, 0.015 mol) and 1,1,1-triethoxy-ethane (5 g, 0.045 mol) were heated for 7 hours. The reaction mixture was poured into water, filtered, and the precipitate was washed with water and recrystallized from EtOH to yield 73 (2.5 g, 75%). M. Wt. 237. LCMS [M+H]+=238.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07893260B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-52413c69eb47490895aba0999c6e30a4 |
| 출처 메모 | uspto-grants-2011_02 |