Triethylamine → HCID 66940621, 화합물

HRID 1367949노트

반응식

HRID 1367949 반응식
[CH3:1][O:2][C:3](=[O:15])[C:4]1[CH:9]=[C:8](F)[CH:7]=[C:6]([NH2:11])[C:5]=1[N+:12]([O-:14])=[O:13].[CH2:16](N(CC)CC)C.[CH3:23][CH2:24][O-:25].[Na+]>C(O)C>[CH2:1]([O:2][C:3](=[O:15])[C:4]1[CH:9]=[C:8]([O:25][CH2:24][CH3:23])[CH:7]=[C:6]([NH2:11])[C:5]=1[N+:12]([O-:14])=[O:13])[CH3:16]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 2723922Sodium ethoxideHCID 58724451Methyl 3-amino-5-fluoro-2-nitrobenzoate

생성물 1

HCID 66940621HCID 66940621, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
60 °C

실험 절차

5.0 g (23.3 mmol) of 3-amino-5-fluoro-2-nitro-benzoic acid methyl ester was dissolved in ethanol and treated with 2.6 g (25.6 mmol) of triethylamine and 1.8 g (25.6 mmol) of NaOEt. The reaction was heated at 60° C. for 0.5 h to produce 3-amino-5-ethoxy-2-nitro-benzoic acid ethyl ester. LCMS: 255 (M+1)+.

출처 및 근거

ORD 기록
ord-2abc8f152b0a40aeb4e52387f205b442
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07893267B2

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