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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1368509생성일: 2026년 10월 27일

Formic Acid → HCID 178487492, 화합물

https://huagongshe.com/reaction/1368509

반응식

참여 물질

역할이름HCID투입량
반응물Formic AcidHCID 284—
반응물TetrahydrofuranHCID 8028—
반응물(6-Methoxynaphthalen-2-yl)-(1-trityl-1H-imidazol-4-yl)ketoneHCID 11733735—
생성물HCID 178487492HCID 178487492—

반응 조건

온도50 °C

반응 단계

(6-Methoxynaphthalen-2-yl)-(1-trityl-1H-imidazol-4-yl)ketone (15.0 g) was dissolved in THF (80 ml). To the solution was added 90% formic acid (20 ml), and the mixture was stirred at 50° C. for 2 h. After removal of the solvents by evaporation, 1N-hydrochloric acid (60 ml) was added and the precipitate was filtered off. The filtrate was washed with ether, and neutralized with potassium carbonate. The resulting precipitate was collected by filtration, dried under reduced pressure to give the titled compound (7.54 g) as a colorless solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06573289B1
출처 데이터셋uspto-grants-2003_06
ORD IDord-6db7d0a9eed2440bbe8e310b76c2ae5a
출처 메모uspto-grants-2003_06