HCID 178418443, 화합물 → HCID 178458200, 화합물

HRID 1368518

반응식

HRID 1368518 반응식
[NH:1]1[CH:5]=[C:4]([C:6]([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)=[O:7])[N:3]=[CH:2]1.[CH2:20]([Mg]Br)[CH3:21]>CCOCC>[NH:1]1[CH:5]=[C:4]([C:6]([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)([OH:7])[CH2:20][CH3:21])[N:3]=[CH:2]1

참가 물질

4

반응물 2

HCID 178418443HCID 178418443, 화합물HCID 178487490HCID 178487490, 화합물

생성물 1

HCID 178458200HCID 178458200, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

In a similar manner to that described in Example 1-(iv), the reaction of (1H-imidazol-4-yl)-(6-methoxynaphthalen-2-yl)ketone (0.60 g) with a solution of ethyl magnesium bromide in ether (3.0 M, 2.4 ml) was carried out to give the titled compound (0.28 g) as a colorless solid.

출처 및 근거

ORD 기록
ord-006147c066884f9d893d45d87d990d82
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06573289B1

연결된 노트

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