HCID 178419650, 화합물 → HCID 178487489, 화합물

HRID 1368520

반응식

HRID 1368520 반응식
[NH:1]1[CH:5]=[C:4]([C:6]([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)=[O:7])[N:3]=[CH:2]1.[CH:20]1([Mg]Br)[CH2:24][CH2:23][CH2:22][CH2:21]1>C1COCC1>[CH:20]1([C:6]([C:4]2[N:3]=[CH:2][NH:1][CH:5]=2)([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)[OH:7])[CH2:24][CH2:23][CH2:22][CH2:21]1

참가 물질

4

반응물 2

HCID 178419650HCID 178419650, 화합물HCID 178487490HCID 178487490, 화합물

생성물 1

HCID 178487489HCID 178487489, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

In a similar manner to that described in Example 1-(iv), the reaction of (1H-imidazol-4-yl)-(6-methoxynaphthalen-2-yl)ketone (0.60 g) with cyclopentylmagnesium bromide in THF (1.0 M, 10 ml) was carried out to give the titled compound (0.80 g) as a colorless solid.

출처 및 근거

ORD 기록
ord-c2b20b9f3d5a4e7789975709a6c15b2c
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06573289B1

연결된 노트

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