Isopropyl iodide → HCID 178458193, 화합물

HRID 1368536노트

반응식

HRID 1368536 반응식
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([C:17]1[N:18]=[CH:19][N:20](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH:21]=1)([OH:16])[CH:13]([CH3:15])[CH3:14])[CH:6]=[CH:5]2.[CH:41](I)([CH3:43])[CH3:42]>>[CH:41]([O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([C:17]1[N:18]=[CH:19][NH:20][CH:21]=1)([OH:16])[CH:13]([CH3:14])[CH3:15])[CH:6]=[CH:5]2)([CH3:43])[CH3:42]

참가 물질

3

반응물 2

HCID 6362Isopropyl iodideHCID 220183856-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthol

생성물 1

HCID 178458193HCID 178458193, 화합물

실험 절차

In a similar manner to that described in Example 31-(i), the reaction of 1-(6-hydroxynaphthalen-2-yl)-2-methyl-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (0.965 g) with isopropyl iodide (0.20 ml) was carried out to give the titled compound (0.548 g) as a colorless solid.

출처 및 근거

ORD 기록
ord-52f35c555a834b23a2173b61a8947fdd
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06573289B1

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