Thionyl Chloride → Methyl 2-chloro-3-chlorocarbonyl-4-methylsulfonylbenzoate
반응식
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[C:15]([C:16](O)=[O:17])=[C:14]([S:19]([CH3:22])(=[O:21])=[O:20])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]>CN(C)C=O.C1(C)C=CC=CC=1>[Cl:5][C:6]1[C:15]([C:16]([Cl:3])=[O:17])=[C:14]([S:19]([CH3:22])(=[O:21])=[O:20])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]참가 물질
5
실험 절차
2 drops of dimethylformamide and 11.9 g (0.1 mol) of thionyl chloride were added to a solution of 6.0 g (0.021 mol) of methyl 2-chloro-3-hydroxycarbonyl-4-methylsulfonylbenzoate and 50 ml of dry toluene. The solution was heated under reflux for 4 hours. After removal of the solvent under reduced pressure, 6.2 g of methyl 2-chloro-3-chlorocarbonyl-4-methylsulfonylbenzoate were obtained.
후처리
- temperatureThe solution was heated
- temperatureunder reflux for 4 hours
- customAfter removal of the solvent under reduced pressure
출처 및 근거
- ORD 기록
- ord-dc418e1dc96e465493303c86af10793d
- 출처 데이터셋
- uspto-grants-2003_06
- 특허 번호
- US06576596B1
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