2,5-Diamino-2-methylpentanoic acid hydrochloride → 2-Amino-5-[[1-(hydroxyimino)ethyl]amino]-2-methylpentanoic Acid, Dihydrochloride
반응식
[ClH:1].[CH3:2][C:3]([C:9]([OH:11])=[O:10])([CH2:5][CH2:6][CH2:7][NH2:8])[NH2:4].[Cl:12][CH2:13][CH:14]=[N:15][OH:16]>O>[ClH:12].[ClH:1].[NH2:4][C:3]([CH3:2])([CH2:5][CH2:6][CH2:7][NH:8][C:14](=[N:15][OH:16])[CH3:13])[C:9]([OH:11])=[O:10]참가 물질
4
실험 절차
α-Methyl-D,L-ornithine hydrochloride is protected as a copper complex via reaction with cupric carbonate in water at reflux. This protected amino acid is then reacted with chloroacetaldoxime as in Example 1. The product is eluted from Dowex with 1N ammonium hydroxide. Concentration in vacuo, followed by acidification with hydrochloric acid affords the title compound.
후처리
- temperatureat reflux
- washThe product is eluted from Dowex with 1N ammonium hydroxide
- concentrationConcentration in vacuo
출처 및 근거
- ORD 기록
- ord-eb06487868184bf3ac67696b73a3afeb
- 출처 데이터셋
- uspto-grants-2003_06
- 특허 번호
- US06576780B1
반응 노트
불러오는 중…