Indole → 3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indole

HRID 13704

반응식

[CH2:1]([C:3]1(O)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].[NH:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15]1>>[CH2:1]([C:3]1([C:16]2[C:17]3[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=3)[NH:14][CH:15]=2)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2]

참가 물질

반응물 2

HCID 798Indole

HCID 593404281-Ethyl-5-fluoroindan-1-ol

생성물 1

HCID 116377043-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indole

실험 절차

Utilizing 1-ethyl-5-fluoro-indan-1-ol and indole, the title compound is prepared as in example 1.89 mg (54%). LC-MS m/z 280.0 (M++1).

출처 및 근거

ORD 기록: ord-571cb003a18244a2853d9d41003ea8b5
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07728150B2

연결된 노트

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