1-(Bromomethyl)-2,4-difluorobenzene → N-{4-[3-(allyloxy)phenoxy]benzyl}-N-(2,4-difluorobenzyl)-N-(3-nitro-2-vinylphenyl)amine
반응식
[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:28]=[CH:29][CH:30]=1)[O:8][C:9]1[CH:27]=[CH:26][C:12]([CH2:13][NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[C:16]=2[CH:24]=[CH2:25])=[CH:11][CH:10]=1)[CH:2]=[CH2:3].[F:31][C:32]1[CH:39]=[C:38]([F:40])[CH:37]=[CH:36][C:33]=1[CH2:34]Br>>[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([CH:28]=[CH:29][CH:30]=1)[O:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:13][N:14]([CH2:34][C:33]2[CH:36]=[CH:37][C:38]([F:40])=[CH:39][C:32]=2[F:31])[C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[C:16]=2[CH:24]=[CH2:25])=[CH:26][CH:27]=1)[CH:2]=[CH2:3]참가 물질
3
실험 절차
The product from Example 87A and 2,4-difluorobenzyl bromide were processed as described in Example 6B to provide the title compound. MS (ESI+) m/z 529 (M+H)+.
출처 및 근거
- ORD 기록
- ord-b01fc0247412465bb72abd5efc9a6681
- 출처 데이터셋
- uspto-grants-2003_06