7-Methoxy-1H-indole → 3-(1-Ethyl-5-fluoro-indan-1-yl)-7-methoxy-1H-indole

HRID 13710

반응식

HRID 13710 반응식
[CH2:1]([C:3]1(O)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].[CH3:14][O:15][C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[NH:23][CH:22]=[CH:21]2>>[CH2:1]([C:3]1([C:21]2[C:20]3[C:24](=[C:16]([O:15][CH3:14])[CH:17]=[CH:18][CH:19]=3)[NH:23][CH:22]=2)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2]

참가 물질

3

반응물 2

HCID 766607-Methoxy-1H-indoleHCID 593404281-Ethyl-5-fluoroindan-1-ol

생성물 1

HCID 589417043-(1-Ethyl-5-fluoro-indan-1-yl)-7-methoxy-1H-indole

실험 절차

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 7-methoxyindole, the title compound is prepared as in example 1. 123 mg (59%). LC-MS m/z 310.2 (M++1).

출처 및 근거

ORD 기록
ord-5204ade0db7a47d9aede56c426b03f2f
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728150B2

연결된 노트

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