2-bromo-4-fluoro-1-isopropoxybenzene → HCID 21070587, 화합물

HRID 1371678노트

반응식

HRID 1371678 반응식
CON(C)[C:4]([C:6]1[C:7]([NH2:15])=[N:8][C:9]([S:12][CH2:13][CH3:14])=[N:10][CH:11]=1)=[O:5].Br[C:18]1[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:19]=1[O:25][CH:26]([CH3:28])[CH3:27]>>[NH2:15][C:7]1[C:6]([C:4]([C:18]2[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:19]=2[O:25][CH:26]([CH3:28])[CH3:27])=[O:5])=[CH:11][N:10]=[C:9]([S:12][CH2:13][CH3:14])[N:8]=1

참가 물질

3

반응물 2

HCID 27733882-bromo-4-fluoro-1-isopropoxybenzeneHCID 119748325-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-

생성물 1

HCID 21070587HCID 21070587, 화합물

실험 절차

The compound was prepared from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide, Example 1, and 2-bromo-4-fluoro-1-isopropoxy-benzene (prepared from 2-bromo-4-fluoro-phenol, Aldrich) in an analogous manner as described in Example 169.

출처 및 근거

ORD 기록
ord-efd8b4df8867479483c9f17470e4ff28
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07157455B2

반응 노트

불러오는 중…