Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Acetyl-5-nitroindolin-2-one → 1-Acetyl-5-aminoindolin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Acetyl-5-nitroindolin-2-one | HCID 2839329 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Acetyl-5-aminoindolin-2-one | HCID 12046998 | — |
반응 단계
30.0 g (136 mmol) of 1-acetyl-5-nitro-2-indolinone are dissolved in a mixture of 650 ml of dichloromethane and 650 ml of methanol and after the addition of 5 g of 10% palladium on activated charcoal the mixture is hydrogenated for 45 minutes with hydrogen. Then the catalyst is filtered off and evaporated down.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07160901B2 |
| 출처 데이터셋 | uspto-grants-2007_01 |
| ORD ID | ord-20d1f7e55882484bb6b38a2f3b1021d2 |
| 출처 메모 | uspto-grants-2007_01 |