Dimethyl malonate → HCID 16637924, 화합물
반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH:10]([CH3:12])[CH3:11])=[CH:5][CH:4]=1.[CH3:13][O:14][C:15](=[O:21])[CH2:16][C:17]([O:19][CH3:20])=[O:18].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[CH3:13][O:14][C:15](=[O:21])[CH:16]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH:10]([CH3:12])[CH3:11])=[CH:5][CH:4]=1)[C:17]([O:19][CH3:20])=[O:18]참가 물질
5
실험 절차
1-(Chloromethyl)-4-(1-methylethoxy)benzene (20.5 g, 111 mmol), malonic acid dimethyl ester (102.5 g, 776 mmol) and potassium carbonate (46.5 g, 332 mmol, anhydrous, freshly ground) are stirred in absolute DMF (250 ml) for 24 hours at 70° C.
출처 및 근거
- ORD 기록
- ord-348b4781162e47d9b7cc0228d2c279e0
- 출처 데이터셋
- uspto-grants-2007_01
- 특허 번호
- US07166588B2
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