2,3-Dichloro-5-hydroxypyridine → 2-(5,6-dichloro-3-pyridyloxy)-N-(4-methylpent-2-yn-4-yl)butyramide

HRID 1374904노트

반응식

HRID 1374904 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[N:6][C:7]=1[Cl:8].Br[CH:11]([CH2:21][CH3:22])[C:12]([NH:14][C:15]([CH3:20])([CH3:19])[C:16]#[C:17][CH3:18])=[O:13]>>[Cl:1][C:2]1[CH:3]=[C:4]([O:9][CH:11]([CH2:21][CH3:22])[C:12]([NH:14][C:15]([CH3:20])([CH3:19])[C:16]#[C:17][CH3:18])=[O:13])[CH:5]=[N:6][C:7]=1[Cl:8]

참가 물질

3

반응물 2

HCID 143916722,3-Dichloro-5-hydroxypyridineHCID 210784062-bromo-N-(4-methylpent-2-yn-4-yl)butyramide

생성물 1

HCID 210783702-(5,6-dichloro-3-pyridyloxy)-N-(4-methylpent-2-yn-4-yl)butyramide

실험 절차

5,6-Dichloropyridin-3-ol was reacted with 2-bromo-N-(4methylpent-2-yn-4-yl)butyramide in a similar procedure to that described in Example 10, Stage 2 to give 2-(5,6-dichloro-3-pyridyloxy)-N-(4methylpent-2-yn-4-yl)butyramide, gum.

출처 및 근거

ORD 기록
ord-e18f7b873f9244578e7e8fc7900561b3
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166621B2

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