2-(5-Chloro-3-pyridyloxy)butyric acid → 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide

HRID 1374910노트

반응식

HRID 1374910 반응식
Cl.[NH2:2][C:3]([CH3:11])([CH3:10])[C:4]#[C:5][CH:6]([O:8][CH3:9])[CH3:7].[Cl:12][C:13]1[CH:14]=[C:15]([O:19][CH:20]([CH2:24][CH3:25])[C:21](O)=[O:22])[CH:16]=[N:17][CH:18]=1>>[Cl:12][C:13]1[CH:14]=[C:15]([O:19][CH:20]([CH2:24][CH3:25])[C:21]([NH:2][C:3]([CH3:11])([CH3:10])[C:4]#[C:5][CH:6]([O:8][CH3:9])[CH3:7])=[O:22])[CH:16]=[N:17][CH:18]=1

참가 물질

3

반응물 2

HCID 210783782-(5-Chloro-3-pyridyloxy)butyric acidHCID 210784255-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

생성물 1

HCID 210783842-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide

실험 절차

5-Amino-2-methoxy-5-methylhex-3-yne hydrochloride was reacted with 2-(5-chloro-3-pyridyloxy)butyric acid in a similar procedure to Example 1, Stage 3 to give 2-(5-chloro-3-pyridyloxy)-N-(2-methoxy-5-methylhex-3-yn-5-yl)butyramide as a yellow oil.

출처 및 근거

ORD 기록
ord-fca56104198a4b5b96d1612f2210f170
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166621B2

반응 노트

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