3-Hydroxy-5-chloropyridine → (5-chloro-3-pyridyloxy)-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamide

HRID 1374919노트

반응식

HRID 1374919 반응식
Br[CH:2]([CH2:14][O:15][CH3:16])[C:3]([NH:5][C:6]([CH3:13])([CH3:12])[C:7]#[C:8][CH2:9][O:10][CH3:11])=[O:4].[Cl:17][C:18]1[CH:19]=[N:20][CH:21]=[C:22]([OH:24])[CH:23]=1>>[Cl:17][C:18]1[CH:23]=[C:22]([O:24][CH:2]([CH2:14][O:15][CH3:16])[C:3]([NH:5][C:6]([CH3:13])([CH3:12])[C:7]#[C:8][CH2:9][O:10][CH3:11])=[O:4])[CH:21]=[N:20][CH:19]=1

참가 물질

3

반응물 2

HCID 5823053-Hydroxy-5-chloropyridineHCID 21078403HCID 21078403, 화합물

생성물 1

HCID 21078428(5-chloro-3-pyridyloxy)-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamide

실험 절차

2-Bromo-N-(1-methoxy-4-methylpent-2-yn-4-yl)-3-methoxypropionamide was reacted with 3-chloro-5-hydroxypyridine in a similar procedure to Example 10, Stage 2 to give the required product as a pale yellow oil.

출처 및 근거

ORD 기록
ord-94aa0232976e4a4db47e4205d36f00bb
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166621B2

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