HCID 23145989, 화합물 → HCID 23145982, 화합물
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[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([CH2:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([O:15]CC)=[O:14])=[CH:11][C:10]=2[C:20]([F:23])([F:22])[F:21])[CH2:4][CH2:3]1>CO>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([CH2:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([OH:15])=[O:14])=[CH:11][C:10]=2[C:20]([F:21])([F:23])[F:22])[CH2:6][CH2:7]1참가 물질
3
시약·촉매·용매 1
실험 절차
This compound was prepared in the same manner as in Reference Example 1 (step 6), except that ethyl 4-(1-methylpiperidin-4-ylmethyl)-3-trifluoromethylbenzoate obtained in the step 1 was used, and that the crude product was mixed with methanol and stirred, insolubles were removed by filtration, the filtrate was distilled off under reduced pressure, and then the residue was crystallized by adding acetonitrile.
후처리
- customobtained in the step 1
- custominsolubles were removed by filtration
- distillationthe filtrate was distilled off under reduced pressure
- customthe residue was crystallized
- additionby adding acetonitrile
출처 및 근거
- ORD 기록
- ord-566edd5b8b8c4f61ba505a198e9a2476
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07728131B2
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