tert-Butyl piperazine-1-carboxylate → HCID 58780713, 화합물

HRID 1376061노트

반응식

HRID 1376061 반응식
[N+:1]([CH:4]=[CH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)([O-:3])=[O:2].[C:12]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>C(Cl)Cl>[C:15]([O:14][C:12]([N:19]1[CH2:24][CH2:23][N:22]([CH:5]([CH:6]2[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:4][N+:1]([O-:3])=[O:2])[CH2:21][CH2:20]1)=[O:13])([CH3:18])([CH3:16])[CH3:17]

참가 물질

4

반응물 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 66992131(2-Nitrovinyl)-cyclohexane

생성물 1

HCID 58780713HCID 58780713, 화합물수율 99%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a solution of (2-nitrovinyl)-cyclohexane (2.63 g, 16.94 mmol), prepared as in J. Org. Chem. 1993, 58, 3850, in dry CH2Cl2 (22 mL), N-Boc piperazine (2.63 g, 14.12 mmol) was added at room temperature and reaction stirred overnight. Solvent was removed under reduced pressure to afford the adduct product (99%) as an oil. MS m/z 342.4 (M++1) .

후처리

  1. customreaction
  2. customSolvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-3d306851976b4c00835fdb3645c9129e
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07169777B2

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