1,3-Dibromopropane → HCID 21883826, 화합물
반응식
[Br:1][CH2:2][CH2:3][CH2:4]Br.C(=O)([O-])[O-].[K+].[K+].[CH:12]1([C:15]([C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)=[O:16])[CH2:14][CH2:13]1>CC(C)=O>[Br:1][CH2:2][CH2:3][CH2:4][O:23][C:20]1[CH:19]=[CH:18][C:17]([C:15]([CH:12]2[CH2:13][CH2:14]2)=[O:16])=[CH:22][CH:21]=1참가 물질
5
실험 절차
To a stirred and heated mixture of 1,3-dibromopropane (5 mmol) and potassium carbonate (3.4 mmol) in acetone (40 ml) was added dropwise a solution of 4-cyclopropanecarbonylphenol (5 mmol) in acetone (20 ml). The reaction was allowed to continue overnight. The mixture was filtered hot and the solvent removed under reduced pressure to leave an oil. The oil was purified by column chromatography on silica gel eluting with petroleum ether/ethyl acetate (15:1).
후처리
- temperatureheated
- filtrationThe mixture was filtered hot
- customthe solvent removed under reduced pressure
- customto leave an oil
- customThe oil was purified by column chromatography on silica gel eluting with petroleum ether/ethyl acetate (15:1)
출처 및 근거
- ORD 기록
- ord-8621293dbb2c495889e7f165a99d30a3
- 출처 데이터셋
- uspto-grants-2007_01
- 특허 번호
- US07169928B2
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