5-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diol → 5-(2-Cyclopentyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

HRID 1376246

반응식

HRID 1376246 반응식
[CH:1]1([C:6]2([C:11]3[CH:16]=[C:15]([O:17]C)[CH:14]=[C:13]([O:19]C)[CH:12]=3)[S:10][CH2:9][CH2:8][S:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.C(C1(C2C=C(O)C=C(O)C=2)SCCS1)CCC>CCCCCC.C(OCC)(=O)C>[CH:1]1([C:6]2([C:11]3[CH:12]=[C:13]([OH:19])[CH:14]=[C:15]([OH:17])[CH:16]=3)[S:7][CH2:8][CH2:9][S:10]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

참가 물질

4

반응물 2

HCID 3176955-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diolHCID 116452612-Cyclopentyl-2-(3,5-dimethoxy-phenyl)-[1,3]dithiolane

생성물 1

HCID 115437405-(2-Cyclopentyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

시약·촉매·용매 1

HCID 21226206Ethyl acetate hexane용매

실험 절차

Compound 17 was prepared from Compound 10 using the same procedure as described above for Compound 16. Yield 0.67 g (74.1%) as a waxy solid. Rf=0.28 (hexane:ethyl acetate 8:2); 1H NMR δ 6.89 (d, J=2.4 Hz, 2H), 6.23 (t, J=2.1 Hz, 1H), 5.68 (br s, 2H), 3.34–3.07 (m, 4H), 2.78–2.67 (m, 1H), 1.71–1.38 (m, 8H); 13C NMR δ 156.26, 150.31, 108.13, 101.59, 79.28, 52.27, 39.02, 31.39, 25.94; MS: (ESI, Pos.) m/z 305 ([M+23]+).

출처 및 근거

ORD 기록
ord-c5a44c3dc8a447deb3e5d11246ab6ec7
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07169942B2

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