5-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diol → 5-(2-Cycloheptyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

HRID 1376248

반응식

HRID 1376248 반응식
[CH:1]1([C:8]2([C:13]3[CH:18]=[C:17]([O:19]C)[CH:16]=[C:15]([O:21]C)[CH:14]=3)[S:12][CH2:11][CH2:10][S:9]2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(C1(C2C=C(O)C=C(O)C=2)SCCS1)CCC>CCCCCC.C(OCC)(=O)C>[CH:1]1([C:8]2([C:13]3[CH:14]=[C:15]([OH:21])[CH:16]=[C:17]([OH:19])[CH:18]=3)[S:9][CH2:10][CH2:11][S:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

참가 물질

4

반응물 2

HCID 3176955-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diolHCID 858840932-Cycloheptyl-2-(3,5-dimethoxy-phenyl)-[1,3]dithiolane

생성물 1

HCID 858841035-(2-Cycloheptyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

시약·촉매·용매 1

HCID 21226206Ethyl acetate hexane용매

실험 절차

Compound 19 was prepared from Compound 12 using the same procedure as described above for Compound 16. Yield 0.582 g (41.5%) as a waxy solid. Rf=0.28 (hexane:ethyl acetate 8:2); 1H NMR δ 6.85 (d, J=2.4 Hz, 2H), 6.22 (t, J=2.25 Hz, 1H), 5.16 (br s, 2H), 3.31–3.07 (m, 4H), 2.35–2.28 (m, 1H), 1.97–1.29 (m, 12H); 13C NMR δ 156.07, 149.33, 107.65, 101.25, 50.92, 39.00, 32.55, 27.70, 27.43; MS: (ESI, Pos.) m/z 333 ([M+23]+).

출처 및 근거

ORD 기록
ord-428698e851d14c1baa0941cd95f51ba6
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07169942B2

연결된 노트

불러오는 중…