5-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diol → 5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

HRID 1376250

반응식

HRID 1376250 반응식
[CH:1]1([C:7]([C:10]2[CH:15]=[C:14]([O:16]C)[CH:13]=[C:12]([O:18]C)[CH:11]=2)([CH3:9])[CH3:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(C1(C2C=C(O)C=C(O)C=2)SCCS1)CCC>CCCCCC.C(OCC)C>[CH:1]1([C:7]([C:10]2[CH:15]=[C:14]([OH:16])[CH:13]=[C:12]([OH:18])[CH:11]=2)([CH3:9])[CH3:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 3176955-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diolHCID 123212881-(2-Cyclohexylpropan-2-yl)-3,5-dimethoxybenzene

생성물 1

HCID 123212925-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

시약·촉매·용매 1

HCID 21584099Diethylether hexane용매

실험 절차

Compound 21 was prepared from Compound 14 using the same procedure as described above for Compound 16. Yield 1.11 g (61.9%) as a viscous oil. Rf=0.28 (hexane:diethyl ether 6:4); 1H NMR δ 6.38 (d, J=2 Hz, 2H), 6.17 (t, J=2.25 Hz, 1H), 4.82 (br s, 2H), 1.71–1.68 (m, 2H), 1.63–1.60 (m, 1H), 1.53–1.51 (m, 2H), 1.42–1.36 (m, 1H), 1.17 (s, 6H), 1.16–1.03(m, 3H), 0.94–0.86 (m, 2H); 13C NMR δ 156.32, 154.45, 106.56, 100.02, 49.21, 40.85, 28.12, 27.39, 26.91, 25.39, 14.40; MS: (ESI, Neg.) m/z 233 ([M−H]−).

출처 및 근거

ORD 기록
ord-2c159bceb97843fdbe6e7d4dc3288c85
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07169942B2

연결된 노트

불러오는 중…