Methylamine → HCID 22918634, 화합물
반응식
[CH2:1]([N:8]1[C:12](Br)=[C:11]([N+:14]([O-:16])=[O:15])[C:10]([Br:17])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][NH2:19]>O>[CH2:1]([N:8]1[C:12]([NH:19][CH3:18])=[C:11]([N+:14]([O-:16])=[O:15])[C:10]([Br:17])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
4
실험 절차
3.61 g (10 mmoles) of 1-benzyl -3,5-dibromo-4-nitropyrazole are heated in 100 ml of a 35-percent solution of methylamine in water for 4 hours at 60° C. After cooling, the separated precipitate is collected by filtration and recrystallized once from ethanol. 2.7 g (87 percent of theory) of 1-benzyl-3-bromo-5-methylamino-4-nitropyrazole are obtained in the form of colorless crystals with a melting point of 116° C.
후처리
- temperatureAfter cooling
- filtrationthe separated precipitate is collected by filtration
- customrecrystallized once from ethanol
출처 및 근거
- ORD 기록
- ord-247c1dad6cd749e790798edac8c27bb3
- 출처 데이터셋
- uspto-grants-1997_09
- 특허 번호
- US05663366
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