Ethane, 1-chloro-1-ethoxy- → N-benzoyl-O-(1-ethoxyethyl)-3-phenyl-isoserine

HRID 1376935

반응식

HRID 1376935 반응식
[C:1]([NH:9][CH:10]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:11]([C:13]([OH:15])=[O:14])[OH:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22]([O:24][CH:25](Cl)[CH3:26])[CH3:23]>C(Cl)Cl>[C:1]([NH:9][CH:10]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:11]([C:13]([O:15][CH:22]([O:24][CH2:25][CH3:26])[CH3:23])=[O:14])[OH:12])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 23478Ethane, 1-chloro-1-ethoxy-HCID 33150463-Benzoylamino-2-hydroxy-3-phenyl-propionic acid

생성물 1

HCID 67714526N-benzoyl-O-(1-ethoxyethyl)-3-phenyl-isoserine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

reacting said N-benzoyl-3-phenyl-isoserine with 1-chloroethyl ethyl ether and tertiary amine in methylene chloride to form-N-benzoyl-O-(1-ethoxyethyl)-3-phenyl-isoserine for the C13 side chain;

출처 및 근거

ORD 기록
ord-02664cdbe13745ea878107ca0f892f73
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05663393

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