Water → 4-Methyl-2-trifluoroacetyloxazole
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[F:1][C:2]([F:11])([F:10])[C:3](N1C=CN=C1)=[O:4].[CH3:12][C:13]1[N:14]=[C:15]([Si](C)(C)C)[O:16][CH:17]=1.O>C(OCC)C>[CH3:12][C:13]1[N:14]=[C:15]([C:3](=[O:4])[C:2]([F:11])([F:10])[F:1])[O:16][CH:17]=1참가 물질
5
실험 절차
1-Trifluoroacetylimidazole (10 g) was added to a stirred solution of 4-methyl-2-trimethylsilyloxazole (J. Chem. Soc., Chem. Commun., 1984, 258) (9.95 g) in diethyl ether (100 ml) at 0° C. After 20 hours, water was added. The organic phase was separated, dried and evaporated and the residue was purified by flash chromatography to give the title compound as the corresponding hydrate.
후처리
- customThe organic phase was separated
- customdried
- customevaporated
- customthe residue was purified by flash chromatography
출처 및 근거
- ORD 기록
- ord-0c8d181e4d924edba3ee1e5515808eb9
- 출처 데이터셋
- uspto-grants-1997_09
- 특허 번호
- US05665747
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