3-Cyano-2,6-dichloro-4-methylpyridine → 4-Methyl-3-cyanopyridine

HRID 1378689

반응식

HRID 1378689 반응식
[C:1]([C:3]1[C:4](Cl)=[N:5][C:6](Cl)=[CH:7][C:8]=1[CH3:9])#[N:2]>[Pd](Cl)Cl.[Pd]>[C:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9])#[N:2]

참가 물질

4

반응물 1

HCID 701313-Cyano-2,6-dichloro-4-methylpyridine

생성물 1

HCID 2278064-Methyl-3-cyanopyridine

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 24290Palladium Chloride촉매

실험 절차

hydrogenating the 3-cyano-2,6-dichloro-4-methylpyridine produced in b) in the presence of an organic solvent, with an hydrogenation catalyst selected from the group consisting of palladium (II) chloride and 10% Pd/C, at 50 to 150 psi, at a temperature of from 20° C. to 100° C., for 6 to 24 hours, to produce 3-cyano-4-methylpyridine;

후처리

  1. customproduced in b) in the presence of an organic solvent

출처 및 근거

ORD 기록
ord-aec8da546a4b41c18a5b9393bce6e4e7
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05668287

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