Acetyl chloride → HCID 178497913, 화합물

HRID 1378699노트

반응식

HRID 1378699 반응식
[C:1](Cl)(=O)C.[OH:5][C:6]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=[C:8]([CH3:15])[N:7]=1>CO>[CH3:1][O:13][C:12]([C:11]1[C:6]([OH:5])=[N:7][C:8]([CH3:15])=[CH:9][CH:10]=1)=[O:14]

참가 물질

4

반응물 2

HCID 6367Acetyl chlorideHCID 178425908HCID 178425908, 화합물

생성물 1

HCID 178497913HCID 178497913, 화합물수율 100%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Acetyl chloride (50 ml) was added cautiously to a stirred suspension of 2-hydroxy-6-methylpyridine-3-carboxylic acid (14.3 g, 93.44 mmol) in dry methanol (500 ml) and the resulting solution was heated to reflux. After 16 h the solution was evaporated in vacuo to give the title compound (15.62 g, 100%) as a solid: 1H NMR (DMSO) shows the methyl singlet at δ 3.71.

후처리

  1. temperaturethe resulting solution was heated to reflux
  2. customAfter 16 h the solution was evaporated in vacuo

출처 및 근거

ORD 기록
ord-9892c3ce260e405e984e4a33138acbd3
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05668289

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