Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tiopronin → 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tiopronin | HCID 5483 | — |
| 반응물 | 4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamide | HCID 462938 | — |
| 생성물 | 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid | HCID 6483559 | 92.3% |
반응 단계
This compound was prepared according to the method of Example 132 using 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.25 g (1.5 mmol) of 2-mercapto-propionylglycine. The product was washed with ether and dried in vacuo to give 0.65 g of the title compound, mp 254°-256° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05668291 |
| 출처 데이터셋 | uspto-grants-1997_09 |
| ORD ID | ord-42fa9b89d0634314929857e1564f52d6 |
| 출처 메모 | uspto-grants-1997_09 |