Ammonium Chloride → HCID 54401849, 화합물

HRID 1378967노트

반응식

HRID 1378967 반응식
[CH2:1]([O:3][P:4]([CH:9]=[CH:10][C:11]1[CH:16]=[CH:15][C:14]([N+:17]([O-])=O)=[CH:13][CH:12]=1)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2].[Cl-].[NH4+]>[Fe]>[CH2:6]([O:5][P:4]([CH:9]=[CH:10][C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)(=[O:8])[O:3][CH2:1][CH3:2])[CH3:7]

참가 물질

4

반응물 2

HCID 25517Ammonium ChlorideHCID 53749636Diethyl [2-(4-nitrophenyl)ethenyl]phosphonate

생성물 1

HCID 54401849HCID 54401849, 화합물

시약·촉매·용매 1

HCID 23925Iron촉매

실험 절차

A suspension containing 4-nitrostyrylphosphonic acid diethyl ester (3.0 g, 10.5 mmol), iron powder (5.58 g, 100 mmol) and ammonium chloride (5.58 g, 104 mmol) is heated to reflux for 45 minutes. The reaction medium is filtered through Celite. The filtrate is concentrated under vacuum and is bipartitioned in a water/dichloromethane mixture. The organic phase is washed with water, then dried (MgSO4) and evaporated under vacuum to give the expected product, which crystallizes gradually.

후처리

  1. temperatureis heated
  2. temperatureto reflux for 45 minutes
  3. filtrationThe reaction medium is filtered through Celite
  4. concentrationThe filtrate is concentrated under vacuum
  5. washThe organic phase is washed with water
  6. dry with materialdried (MgSO4)
  7. customevaporated under vacuum

출처 및 근거

ORD 기록
ord-1d84d78604e14006bc7cc888c2d45c30
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05670493

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