N4-Benzoyl-2'-deoxycytidine → N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

HRID 1379764

반응식

[C:1]([NH:9][C:10]1[CH:23]=[CH:22][N:13]([C@@H:14]2[O:21][C@H:18]([CH2:19][OH:20])[C@@H:16]([OH:17])[CH2:15]2)[C:12](=[O:24])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N#N.C([C@@]1(N2C3N=C(N)NC(=O)C=3N=C2)O[C@H](CO[C:39]([C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)([C:48]2[CH:53]=[CH:52][C:51]([O:54][CH3:55])=[CH:50][CH:49]=2)[C:40]2[CH:45]=[CH:44][C:43]([O:46][CH3:47])=[CH:42][CH:41]=2)[C@@H](O)C1)(=O)C(C)C>>[C:1]([NH:9][C:10]1[CH:23]=[CH:22][N:13]([C@@H:14]2[O:21][C@H:18]([CH2:19][O:20][C:39]([C:56]3[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=3)([C:48]3[CH:53]=[CH:52][C:51]([O:54][CH3:55])=[CH:50][CH:49]=3)[C:40]3[CH:41]=[CH:42][C:43]([O:46][CH3:47])=[CH:44][CH:45]=3)[C@@H:16]([OH:17])[CH2:15]2)[C:12](=[O:24])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 9797617N4-Benzoyl-2'-deoxycytidine

HCID 136395924HCID 136395924, 화합물

생성물 1

HCID 2724490N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

실험 절차

This compound was prepared from N4 -benzoyl-2'-deoxycytidine by the same procedure used for the preparation of N2 -isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine.

출처 및 근거

ORD 기록: ord-4b6a07ba80b645b387fd525a5a2b5920
출처 데이터셋: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05672697

연결된 노트

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