Adenosine, N-benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy- → HCID 67563215, 화합물

HRID 1379774노트

반응식

HRID 1379774 반응식
[F:1][C@H:2]1[C@H:6]([OH:7])[C@@H:5]([CH2:8][OH:9])[O:4][C@H:3]1[N:10]1[CH:18]=[N:17][C:16]2[C:11]1=[N:12][CH:13]=[N:14][C:15]=2[NH:19][C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.C(NC1C2N=CN(C=2N=CN=1)[C@@H]1O[C@H](CO[C:49]([C:66]2[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=2)([C:58]2[CH:63]=[CH:62][C:61]([O:64][CH3:65])=[CH:60][CH:59]=2)[C:50]2[CH:55]=[CH:54][C:53]([O:56][CH3:57])=[CH:52][CH:51]=2)[C@@H](O)C1)(=O)C1C=CC=CC=1>>[CH3:65][O:64][C:61]1[CH:60]=[CH:59][C:58]([C:49]([O:9][CH2:8][C@H:5]2[O:4][C@@H:3]([N:10]3[CH:18]=[N:17][C:16]4[C:11]3=[N:12][CH:13]=[N:14][C:15]=4[NH:19][C:20](=[O:27])[C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)[C@@H:2]([F:1])[C@@H:6]2[OH:7])([C:66]2[CH:67]=[CH:68][CH:69]=[CH:70][CH:71]=2)[C:50]2[CH:55]=[CH:54][C:53]([O:56][CH3:57])=[CH:52][CH:51]=2)=[CH:63][CH:62]=1

참가 물질

3

반응물 2

HCID 2724489Adenosine, N-benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy-HCID 53883372N-(9-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

생성물 1

HCID 67563215HCID 67563215, 화합물

실험 절차

This compound is prepared from 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-N6 -benzoyladenine by the same procedure used for the preparation of N6 -benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine.

출처 및 근거

ORD 기록
ord-ab7517ff13614891ac7266d8fd6a5e5b
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05672697

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