4(Fluoromethyl-ethyl)-nitrobenzene → 4(1-Fluoromethyl-ethyl)-aniline

HRID 1379973노트

반응식

HRID 1379973 반응식
[F:1][CH2:2][CH:3]([C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-])=O)=[CH:7][CH:6]=1)[CH3:4]>CO.[Pd]>[F:1][CH2:2][CH:3]([C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)[CH3:4]

참가 물질

4

반응물 1

HCID 131873674(Fluoromethyl-ethyl)-nitrobenzene

생성물 1

HCID 131873684(1-Fluoromethyl-ethyl)-aniline

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

10.3 g (0.057 Mol) 4(1-fluoromethyl-ethyl)-nitrobenzene are dissolved in 250 ml absolute CH3OH and hydrogenated at room temperature and atmospheric pressure in the presence of 0.61 g 10% Pd/C.

출처 및 근거

ORD 기록
ord-7ba063574cf745628233321543db1a15
출처 데이터셋
uspto-grants-1986_04
특허 번호
US04579585

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