참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | N-Phenylglycine | HCID 66025 | — |
| 반응물 | Potassium cyanate | HCID 11378442 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-Phenylimidazolidine-2,4-dione | HCID 570576 | 24.5% |
반응 단계
A solution of N-phenylglycine (Fluka) (30.2 g, 0.2 moles) in 900 ml of water and 1 ml of acetic acid was heated to 60° C. After thirty minutes potassium cyanate (16.2 g, 0.2 moles) in 100 ml of water was added. Heating was continued for 90', then 25 ml of 37% hydrochloric acid were added and the reaction mixture was heated for 15 h at 90° C. After cooling the precipitate was filtered and crystallized from 95% ethanol. 8.65 g of 1-phenylhydantoin were obtained, m.p. 197°-198°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04579861 |
|---|
| 출처 데이터셋 | uspto-grants-1986_04 |
|---|
| ORD ID | ord-0a835e460ff94148a71c2fd8497e562b |
|---|
| 출처 메모 | uspto-grants-1986_04 |
|---|
